Abstract
An infant girl with failure to thrive and bilateral retinoblastoma had a translocation of the long arm of chromosome 13 to the short arm of the X chromosome, and possible loss of a portion of the q 14 band. The lack of other major organ malformations in this patient emphasized the importance of considering chromosomal aberrations as a possible etiology of retinoblastoma in patients with nonspecific psychomotor retardation.
MeSH terms
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Adult
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Child
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Child, Preschool
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Chromosome Aberrations / complications*
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Chromosome Disorders
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Chromosomes, Human, 13-15
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Cryosurgery
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Eye Neoplasms / complications*
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Eye Neoplasms / etiology
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Eye Neoplasms / pathology
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Female
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Growth Disorders / complications
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Humans
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Infant
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Infant, Low Birth Weight
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Infant, Newborn
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Karyotyping
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Male
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Ophthalmologic Surgical Procedures
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Pregnancy
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Retinoblastoma / complications*
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Retinoblastoma / pathology
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X Chromosome