Abstract
CBP and p300 are versatile coactivators that physically connect many DNA-binding factors to the basal transcription machinery. Phosphorylation by cyclin-dependent or signal-induced protein kinases may regulate their function.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Acetyltransferases*
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Animals
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CREB-Binding Protein
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Cell Cycle Proteins / metabolism*
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Cyclic AMP / metabolism
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Histone Acetyltransferases
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Nuclear Proteins / metabolism*
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Phosphorylation
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Protein Kinases / metabolism
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Trans-Activators*
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Transcription Factors / metabolism*
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Transcription, Genetic*
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p300-CBP Transcription Factors
Substances
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Cell Cycle Proteins
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Nuclear Proteins
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Trans-Activators
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Transcription Factors
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Cyclic AMP
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Acetyltransferases
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CREB-Binding Protein
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Histone Acetyltransferases
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p300-CBP Transcription Factors
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p300-CBP-associated factor
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Protein Kinases