Abstract
A patient with idiopathic hypogonadotropic hypogonadism (IHH) had an apparently balanced reciprocal translocation involving chromosomes 13 and 16 [t(13;16)(q14.11;q24)]. The patient's father has the same chromosomal translocation with no apparent physical abnormalities. The role of the chromosomal translocation in this patient is discussed.
MeSH terms
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Adult
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Chromosome Aberrations / genetics*
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Chromosome Disorders
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Chromosomes, Human, Pair 13 / ultrastructure*
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Chromosomes, Human, Pair 16 / ultrastructure*
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Ejaculation
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Erectile Dysfunction / genetics*
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Follicle Stimulating Hormone / deficiency
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Gonadotropin-Releasing Hormone / deficiency*
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Humans
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Hypogonadism / genetics*
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Kallmann Syndrome / genetics
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Luteinizing Hormone / deficiency
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Male
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Pedigree
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Pituitary Hormone-Releasing Hormones
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Testosterone / deficiency
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Translocation, Genetic*
Substances
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Pituitary Hormone-Releasing Hormones
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Gonadotropin-Releasing Hormone
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Testosterone
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Luteinizing Hormone
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Follicle Stimulating Hormone