Abstract
The remarkably high level of cystic fibrosis mutations among Caucasians may be due to a reduction in heterozygotes in the severity of the diarrhea caused by enterotoxic bacteria.
MeSH terms
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Chlorides / metabolism
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Cystic Fibrosis / genetics*
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Cystic Fibrosis Transmembrane Conductance Regulator
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Diarrhea / microbiology*
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Diarrhea / mortality
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Enterotoxins / physiology*
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Escherichia coli Infections / physiopathology*
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Genetic Predisposition to Disease
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Heterozygote*
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Humans
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Membrane Proteins / genetics
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Membrane Proteins / physiology*
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Models, Biological
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Selection, Genetic
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White People / genetics*
Substances
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CFTR protein, human
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Chlorides
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Enterotoxins
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Membrane Proteins
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Cystic Fibrosis Transmembrane Conductance Regulator