Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization

Cytogenet Cell Genet. 1987;45(2):109-12. doi: 10.1159/000132439.

Abstract

TCP1, the human homolog of the Tcp-1 locus in the mouse, which is part of the murine t complex and codes for an abundant testicular germ-cell protein, has been mapped within the human genome by in situ hybridization. Using a cDNA probe for TCP1, pB1.4 hum, we assigned TCP1 to human chromosome region 6q23----qter, with the most likely localization being 6q25----q27.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 6*
  • DNA / genetics
  • Genetic Linkage
  • Genetic Markers
  • Humans
  • Intracellular Signaling Peptides and Proteins*
  • Karyotyping
  • Mice
  • Microtubule-Associated Proteins*
  • Nuclear Proteins*
  • Nucleic Acid Hybridization
  • Proteins / genetics*
  • Species Specificity
  • Testicular Hormones / genetics*
  • Ubiquitin-Protein Ligases
  • t-Complex Genome Region

Substances

  • Genetic Markers
  • Intracellular Signaling Peptides and Proteins
  • Microtubule-Associated Proteins
  • Nuclear Proteins
  • Proteins
  • Testicular Hormones
  • DNA
  • PPP1R11 protein, human
  • Ubiquitin-Protein Ligases