Deletion of the tumor-suppressor gene NF1 occurs in 5% of myeloid malignancies and is accompanied by a mutation in the remaining allele in half of the cases

MeSH terms

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Alleles*
• Core Binding Factor Alpha 2 Subunit / genetics
• Female
• Gene Deletion*
• Genes, Tumor Suppressor*
• Humans
• In Situ Hybridization, Fluorescence
• Leukemia, Myeloid / genetics*
• Male
• Middle Aged
• Mutation*
• Neurofibromin 1 / genetics*
• Neurofibromin 1 / physiology