Newly recognized syndrome of cerebral, ocular, dental, auricular, skeletal anomalies: CODAS syndrome--a case report

Am J Med Genet. 1991 Jul 1;40(1):88-93. doi: 10.1002/ajmg.1320400118.

Abstract

We report on a child with a unique constellation of congenital anomalies suggesting a new syndrome. These consist of developmental delay; craniofacial abnormalities, including bilateral cataracts, ptosis, median nasal groove, malformed ears with associated neurosensory hearing loss; dental anomalies consisting of anomalous cusp morphology with unusual pointed extensions and delayed tooth eruption; short stature with marked delay in epiphyseal ossification; coronal clefts involving vertebrae T11-S2; and dislocated hips. A literature search and use of a computer-assisted syndrome-identification program failed to uncover an identical case.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / classification*
  • Abnormalities, Multiple / diagnostic imaging
  • Bone and Bones / abnormalities
  • Eye Abnormalities / classification
  • Facial Bones / abnormalities
  • Female
  • Humans
  • Infant
  • Radiography
  • Skull / abnormalities
  • Syndrome
  • Tooth Abnormalities / classification
  • Ultrasonography