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A radical solution to death

Nature Genetics volume 25, pages 132–134 (2000)Cite this article

The Saccharomyces cerevisiae gene SGS1 encodes a protein related to the human DNA helicases defective in Werner syndrome, Bloom syndrome and Rothmund-Thomson syndrome. Yeast cells lacking the Sgs1 helicase and a related helicase, Srs2, are inviable or grow extremely poorly. The growth defect can be rescued by crippling the homologous recombination repair pathway, indicating that the essential function of these genes is related to recombination

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  1. Department of Biochemistry, New York University School of Medicine, 550 First Avenue, New York, 10016, New York, USA

    Hannah L Klein

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  1. Hannah L Klein
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Klein, H. A radical solution to death. Nat Genet 25, 132–134 (2000). https://doi.org/10.1038/75957

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