Current Biology
Volume 8, Issue 19, 24 September 1998, Pages R679-R682
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Bone remodelling: A signalling system for osteoclast regulation

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Abstract

Two physiological regulators of osteoclast maturation have recently been identified: the secreted protein osteoprotegerin and the cell-surface ligand to which it binds. These proteins are likely to play an important part in the control of bone resorption, but are also likely to have important roles in other tissues.

Cited by (0)

E Filvaroff, Department of Endocrinology, Genentech, South San Francisco, California 94080-4990, USA.

R Derynck, Departments of Growth and Development, and Anatomy, Programs in Cell Biology and Developmental Biology, University of California at San Francisco, San Francisco, California 94143, USA.