The incidence of oral clefts: a review

doi:10.1016/S0266-4356(96)90242-9

British Journal of Oral and Maxillofacial Surgery

Volume 34, Issue 6, December 1996, Pages 488-494

https://doi.org/10.1016/S0266-4356(96)90242-9 Get rights and content

Abstract

We have reviewed epidemiological studies on the incidence of oral clefts in several regions of the world, but mainly in Europe. The incidence ranges from 1.0/1000 to 2.21/1000. The highest incidence was in Czechoslovakia (1.81/1000), followed by France (1.75/1000), Finland (1.74/1000), Denmark (1.69/1000), Belgium and the Netherlands (1.47/1000), Italy (1.33/1000), California (1.12/1000) and South America (1.0/1000). The data from Denmark and Finland appeared to be the most reliable.

All studies showed a higher incidence of cleft lip and/or palate (CL(P)) compared with cleft palate (CP). There was a predominance of girls in the CP group, while the CL(P) group comprised mainly boys. The left side was affected twice as often as the right side. Black children had a lower incidence than white children. An attempt was made in several reports to clarify the cause of oral clefts, but opinions are contradictory.

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Citation Excerpt :
Orofacial clefts are one of the most common congenital birth defects with a worldwide frequency of 1 in 700 newborns, [1,2] and an incidence of 1.47/1000 in Belgium and the Netherlands in particular [3].
To investigate a potential delay in dental development in cleft patients compared with non-cleft patients.
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View full text

The incidence of oral clefts: a review

Abstract

Incidence and prevalence as measures of the frequency of congenital malformations and genetic outcomes: Application to oral clefts

Cleft Pal J

Epidemiology: principles and methods

Fetal malformations

Malformations in children from one to seven years

Malformations in children from one to seven years

Malformations in children from one to seven years

Incidence and prevalence as measures of the frequency of birth defects

Am J Epidemiol

Incidence and prevalence of cleft lip and palate: What we think we know

Cleft Pal J

Validity of the birth certificate in the epidemiologic assessment of facial clefts

J Dent Res

Accuracy of birth certificate data for detecting facial cleft defects in Arkansas children

Cleft Palate J

Vital record incidence of congenital malformations in New York State

Cleft lip and palate

De incidentie van cheilognathopalatoschisis in Nederland

Tijdschr Kindergen

Inheritance of harelip and cleft palate

Enquête aangeboren afwijkingen 1963

Schisis in Nederland. De vraag naar behandeling van schisispatienten

Ndl Tijdschr THK

Cleft lip and palate in Denmark, '76–'81: Epidemiology, variability, and early somatic development

Cleft Pal J

Inheritance of harelip and cleft palate

Increasing incidence of clefts in Finland: Reliability of hospital records and central register of congenital malformations

Scand J Plast Reconstr Surg

Seasonality, incidence, and sex distribution of cleft lip and palate births in Trent Region ('73–'82)

Cleft Pal J

Epidemiological and genetic study in 207 cases of oral clefts in Alsace, NorthEastern France

J Med Genet