Review of oxymetholone: a 17α-alkylated anabolic-androgenic steroid
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2019, Forensic Science InternationalCitation Excerpt :Oxymetholone belongs to the 17α alkylated group of AASs and, therefore, cannot be inactivated by the first-pass liver metabolism when consumed orally. However, the alkylation in the 17α position also enhanced the risk of hepatotoxicity of oxymetholone which made the compound controlled worldwide [26,28]. Lastly, for Product #2 bands such as OH (3512 cm-1) and C O (1716 cm-1) were observed (Fig 9S).
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2018, Journal of EthnopharmacologyCitation Excerpt :The administration was performed in a volume of 10 mL/kg once a day for 28 days. The doses of oxymetholone and SFe were based on previous studies (Kim et al., 2015a, 2015b; Pavlatos et al., 2001). Forced swimming was conducted in a circular pool (diameter, 100 cm; height, 30 cm) containing warm water (temperature, 28 ± 1 °C) to a 15-cm depth for 2 min a day, as described elsewhere (Hong et al., 2015).