Case CondensationsAortic Dissection and Myocardial Infarction in a Pregnant Patient with Turner Syndrome
Section snippets
Case
A 33-year-old white primigravida underwent in vitro fertilization with a donor egg. Her medical history was significant for Turner syndrome and hypertension. The patient had been admitted to a local hospital at 24 weeks’ gestation complaining of nausea, vomiting, and worsening epigastric pain over a 2-day period. She began intravenous magnesium sulfate for presumed preeclampsia and subsequently developed acute pulmonary edema. She was transferred to New York Hospital for further care. Her pulse
Comment
Recent advances in reproductive technology have enabled many women to conceive. These include women with serious medical and genetic conditions. We are becoming aware only now of the potential problems of pregnancy for some of these women. Preconceptual counseling and medical evaluation should be performed before conception in these cases.
References (4)
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Turner’s syndrome—Review of the literature with reference to a successful pregnancy outcome
Gynecol Obstet Invest
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A fertile woman with non-mosaic Turner’s. Case report and review of the literature
Br J Obstet Gynaecol
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Cited by (46)
Turner Syndrome and Fertility
2022, Annales d'EndocrinologieCitation Excerpt :Women with TS are predisposed for a wide range of cardiovascular diseases such as hypertension, bicuspid aortic valve and aortic aneurisms and dissections [10,69,70]. All risk factors for adverse outcomes during a pregnancy, and aortic aneurisms can be a fatal pregnancy complication [71,72]. However, newer reports on pregnancy outcomes in women with Turner syndrome from France (n = 480), Canada, USA and the Netherlands (n = 68), and Finland, Denmark and Sweden (n = 106) reported either none or very few cardiovascular events, with a total of only one case of aortic dissection [13,73,74].
Should women with Turner syndrome be allowed to carry their own pregnancies?
2019, Fertility and SterilityLive birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45,XO/46,XX mosaicism) and discordant ovarian function
2011, Fertility and SterilityCitation Excerpt :Finally, the present case demonstrates the strength of the desire of these patients to conceive, despite the known risks. Several deaths with aortic dissection have been reported in Turner syndrome patients, who became pregnant through oocyte donation (43–47). Karnis et al. estimated that at least four deaths occurred in approximately 200 donor oocyte pregnancies in women with Turner syndrome.
Procreation in Turner's syndrome: Which recommendations before, during and after pregnancy?
2008, Gynecologie Obstetrique et Fertilite