Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx
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Cited by (85)
Cytochrome P450 in Cancer Susceptibility and Treatment
2015, Advances in Clinical ChemistryCitation Excerpt :In an Indian study, HNC patients with CYP2D6∗ 4 allele presented with increased risk, while those with CYP2D6∗ 10 allele showed no change or even a small decrease in risk when compared to consumers of tobacco or alcohol and nonconsumers [142]. Another study from Spain and Germany reported that CYP2D6 ultrarapid metabolizer patients had increased risk of developing HNC [143,144]. CYP2E1 polymorphism in HNC susceptibility has been studied with conflicting results.
Lack of association between glutathione S-transferase T1 gene polymorphism and laryngeal cancer susceptibility: A meta-analysis based on 2,124 cases and 2,059 controls
2012, GeneCitation Excerpt :With the step of screening the title or abstract, 20 eligible studies were selected. Of the 20 articles selected, 6 studies were excluded because of the lack of data about GSTT1 status of laryngeal cancer (Boccia et al., 2008; Cabelguenne et al., 2001; Gronau et al., 2003; Li et al., 2009; Olshan et al., 2000; Peters et al., 2006), the study by Jahnke et al, (1996) was excluded because the subjects had been included by the study of Jahnke et al. (1997), the study by Hanna et al. (2001) was excluded because polymorphism was determined in fresh frozen tissue specimens. Finally, 12 studies (Acar et al., 2006; Chatzimichalis et al., 2010; Gajecka et al., 2005; Hong et al., 2000; Jahnke et al., 1995, 1997; Jourenkova et al., 1998; Matthias et al., 1998; Risch et al., 2003; Tian et al., 2011; To-Figueras et al., 2002; Unal et al., 2004) including 2124 laryngeal SCC cases and 2059 controls were included in this meta-analysis based on inclusion and exclusion criteria (Table 1).
Gene polymorphisms and risk of head and neck squamous cell carcinoma: a systematic review
2022, Reports of Practical Oncology and RadiotherapyDo we know enough about the genetic involvement in laryngeal cancer susceptibility and prognostic outcome?
2019, Romanian Journal of Morphology and Embryology