cAMP-dependent protein kinase: role in normal and malignant growth☆
References (311)
Protein kinase
Curr Top Cell Regul
(1972)- et al.
Epidermal growth factor-receptor-protein kinase interactions
J Biol Chem
(1980) - et al.
Activity phosphorylating tyrosine in polyoma T-antigen immunoprecipitates
Cell
(1979) - et al.
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
J Biol Chem
(1982) - et al.
Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation
J Biol Chem
(1983) - et al.
Phospholipid turnover as a possible transmembrane signal for protein phosphorylation during human platelet activation by thrombin
Biochem Biophys Res Commun
(1980) - et al.
Mammalian Ras interacts directly with the serine/threonine kinase Raf
Cell
(1993) - et al.
Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth
FEBS Lett
(1987) - et al.
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site-selective cAMP analogs, antisense strategy, and gene transfer
Life Sci
(1991) - et al.
8-Cl-cAMP induces truncation and down-regulation of the RIα subunit and upregulation of the RIIβ subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells
J Biol Chem
(1993)
Cyclic nucleotide-dependent protein kinases
Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches
Recent Prog Horm Res
(1988)
A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase
J Biol Chem
(1986)
Reversible autophosphorylation of a cyclic 3′,5′-AMP-dependent protein kinase from bovine cardiac muscle
J Biol Chem
(1975)
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase
J Biol Chem
(1986)
The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence
J Biol Chem
(1987)
Evidence that rabbit muscle protein kinase has two kinetically distinct binding sites for adenosine 3′,5′-cyclic monophosphate
Biochem Biophys Res Commun
(1978)
Two different intrachain cAMP binding sites of cAMP-dependent protein kinases
J Biol Chem
(1980)
Studies on the function of the two intrachain cAMP binding sites of protein kinase
J Biol Chem
(1981)
Probable involvement of both intrachain cAMP binding sites in activation of protein kinase
J Biol Chem
(1983)
Identification of a ternary complex between cAMP and a trimeric form of cAMP-dependent protein kinase
J Biol Chem
(1986)
Dissecting the domain structure of the regulatory subunit of cAMP-dependent protein kinase I and elucidating the role of MgATP
J Biol Chem
(1990)
Effect of cAMP and ATP on the reassociation of phosphorylated and non-phosphorylated subunits of the cAMP-dependent protein kinase from bovine cardiac muscle
J Biol Chem
(1977)
Purification and characterization of an inactive form of cAMP-dependent protein kinase containing bound cAMP
J Biol Chem
(1987)
Activation of type I cyclic AMP-dependent protein kinases with defective cyclic AMP-binding sites
J Biol Chem
(1987)
Characterization of the interchain and interchain interactions between the binding sites of the free regulatory moiety of protein kinase I
J Biol Chem
(1984)
Comparison of adenosine 3′,5′-monophosphate-dependent protein kinase from rabbit skeletal and bovine heart muscle
J Biol Chem
(1975)
The distribution and dissociation of cyclic adenosine 3′,5′-monophosphate-dependent protein kinases in adipose, cardiac, and other tissues
J Biol Chem
(1975)
Two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes
J Biol Chem
(1984)
Discriminative insulin antagonism of stimulatory effects of various cAMP analogs on adipocyte lipolysis and hepatocyte glycogenolysis
J Biol Chem
(1985)
cAMP-dependent protein kinase activation lowers hepatocyte cAMP
J Biol Chem
(1985)
Compartmentation of second messenger action: immunocytochemical and biochemical evidence
Vitam Horm
(1985)
Cyclic nucleotide-dependent protein kinases
Pharmacol Ther
(1991)
cAMP-dependent protein kinase
J Biol Chem
(1989)
Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues
J Biol Chem
(1977)
Differences in properties of cytosol and membrane-derived protein kinases
J Biol Chem
(1976)
Cyclic adenosine 3′,5′-monophosphate-dependent protein kinase of human erythrocyte membranes
J Biol Chem
(1972)
Purification and properties of a protein kinase from bovine corpus luteum that is stimulated by cyclic adenosine 3′,5′-monophosphate and luteinizing hormone
J Biol Chem
(1973)
Characterization and localization of cAMP-dependent protein kinases in rat candal epididymal sperm
J Biol Chem
(1984)
Molecular biology of cellular membranes with applications to immunology
Adv Immunol
(1974)
Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2
J Biol Chem
(1982)
Identification of two subclasses of type II cAMP-dependent protein kinases
J Biol Chem
(1980)
Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2
Neuron
(1989)
The RII subunit of cAMP-dependent protein kinase binds to a common aminoterminal domain in microtubule-associated proteins 2A, 2B, and 2C
Neuron
(1989)
Differential binding of the regulatory subunits (RII) of cAMP-dependent protein kinase II from bovine brain and muscle to RII-binding proteins
J Biol Chem
(1986)
Cyclic AMP
(1971)
Studies on the mechanism of hormone action
Science
(1972)
Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor
Nature
(1982)
Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I
Nature
(1983)
Insulin stimulates the phosphorylation of the 95 000-dalton subunit of its own receptor
Science
(1982)
Cited by (132)
Non-transcriptional processes in circadian rhythm generation
2018, Current Opinion in PhysiologyCarney complex review: Genetic features
2018, Endocrinologia, Diabetes y NutricionSelective inhibition of cell death in malignant vs normal B-cell precursors: Implications for cAMP in development and treatment of BCP-ALL
2013, BloodCitation Excerpt :Several lines of evidence indicate that PKAI activity is associated with growth and proliferation, whereas PKAII activity is associated with differentiation and decreased proliferation.39,40 Consistent with this, the RIα subunit has been found to be upregulated in a number of cell lines as well as in primary tumor cells.41,42 Furthermore, a number of human cancer tissues of different origins have been shown to express an increased RI to RII ratio.43
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This paper was reviewed by Theodore Puck, Ph.D., Eleanor Roosevelt Institute for Cancer Research, University of Colorado, Denver, CO 80206, USA.
Copyright © 1995 Published by Elsevier Ireland Ltd.