A new nomenclature for the laminins

doi:10.1016/0945-053X(94)90184-8

Matrix Biology

Volume 14, Issue 3, April 1994, Pages 209-211

https://doi.org/10.1016/0945-053X(94)90184-8 Get rights and content

Abstract

The authors have adopted a new nomenclature for the laminins. They are numbered with arabic numerals in the order discovered. The previous A, B1 and B2 chains, and their isoforms, are α, β and γ, respectively, followed by an arabic numeral to identify the isoform. For example, the first laminin identified from the Engelbreth-Holm-Swarm tumor is laminin-1 with the chain composition α1β1γ1. The genes for these chains are LAMA1, LAMB1 and LAMC1, respectively.

References (1)

R. Timpl et al.
The laminins
Matrix Biol.
(1994)

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Laminins are a family of large molecular weight glycoproteins that accumulate mainly in the ECM of neuroretinal, skeletal or epithelial cells [5]. Electron microscope observation has revealed that these molecules are composed of an α-chain, a β-chain and a γ-chain, and they usually form a cross-shaped structure [6]. Laminin 5 is constructed exclusively out of the α3 (LAMA3), β3 (LAMB3) and γ2 (LAMC2) subunits.
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NomenclatureA new nomenclature for the laminins

Abstract

The laminins

Matrix Biol.

Nomenclature
A new nomenclature for the laminins