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Three cases of subungual glomus tumors with von Recklinghausen neurofibromatosis

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Cited by (39)

  • Glomus tumor: a comprehensive review of the clinical and histopathologic features with report of two intraoral cases

    2019, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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    At least 3 cases of multiple glomus tumors (glomuvenous malformations) affecting the oral regions have been described.9,23,25 Notably, multiple glomus tumors have been associated with neurofibromatosis type I.16,63,64 Multiple occurrences have been linked to chromosome 1p21Y22 (the glomulin gene) and demonstrate an autosomal dominant inheritance pattern with variable expressivity and incomplete (approximately 90%) penetrance. 23,48,57,65,66 The treatment for glomus tumors is excision.

  • Glomus tumors in individuals with neurofibromatosis type 1

    2014, Journal of the American Academy of Dermatology
  • The association between glomus tumors and neurofibromatosis

    2013, Journal of Hand Surgery
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    In 1938, Klaber12 provided the first description of a glomus tumor in a patient with neurofibromatosis, and reported a 13 year-old girl with type 1 neurofibromatosis who underwent excision of a glomus tumor on the leg. Sawada et al13 reported 3 patients with type 1 neurofibromatosis and subungual glomus tumors. Two of the 3 patients had multiple glomus tumors.

  • Benign subungual tumors

    2012, Journal of Hand Surgery
    Citation Excerpt :

    Patients are typically between 30 and 50 years of age at diagnosis,1 with a female predominance noted.2 Single or multiple glomus tumors have rarely been reported to be associated with neurofibromatosis type 1.3–5 These tumors present as intensely painful masses associated with point tenderness, cold sensitivity, nail ridging, and purple or blue nail discoloration1,6 (Fig. 1).

  • Magnetic resonance imaging of benign soft tissue neoplasms in adults

    2011, Radiologic Clinics of North America
    Citation Excerpt :

    There is no gender predilection overall, but there is a 3:1 female predominance for subungual lesions.129 Multiple glomus tumors (nearly 10% of patients) may be present in NF1.130,131 The lesion is most frequently diagnosed between 20 and 40 years of age.

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