Journal of the American Academy of Dermatology
Brief communicationThree cases of subungual glomus tumors with von Recklinghausen neurofibromatosis
References (11)
- et al.
Characterization of a translocation within the von Recklinghausen neurofibromatosis region of chromosome 17
Genomics
(1989) - et al.
Detections and translocation interrupt a cloned gene at the neurofibromatosis type 1 locus
Cell
(1990) Clinical and population genetics: neurofibromatosis
Neurofibromatosis: research on heterogeneity
- et al.
Multiple glomus tumors
Jpn J Dermatol
(1962)
Cited by (39)
Glomus tumor: a comprehensive review of the clinical and histopathologic features with report of two intraoral cases
2019, Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyCitation Excerpt :At least 3 cases of multiple glomus tumors (glomuvenous malformations) affecting the oral regions have been described.9,23,25 Notably, multiple glomus tumors have been associated with neurofibromatosis type I.16,63,64 Multiple occurrences have been linked to chromosome 1p21Y22 (the glomulin gene) and demonstrate an autosomal dominant inheritance pattern with variable expressivity and incomplete (approximately 90%) penetrance. 23,48,57,65,66 The treatment for glomus tumors is excision.
Glomus tumors in individuals with neurofibromatosis type 1
2014, Journal of the American Academy of DermatologyThe association between glomus tumors and neurofibromatosis
2013, Journal of Hand SurgeryCitation Excerpt :In 1938, Klaber12 provided the first description of a glomus tumor in a patient with neurofibromatosis, and reported a 13 year-old girl with type 1 neurofibromatosis who underwent excision of a glomus tumor on the leg. Sawada et al13 reported 3 patients with type 1 neurofibromatosis and subungual glomus tumors. Two of the 3 patients had multiple glomus tumors.
Benign subungual tumors
2012, Journal of Hand SurgeryCitation Excerpt :Patients are typically between 30 and 50 years of age at diagnosis,1 with a female predominance noted.2 Single or multiple glomus tumors have rarely been reported to be associated with neurofibromatosis type 1.3–5 These tumors present as intensely painful masses associated with point tenderness, cold sensitivity, nail ridging, and purple or blue nail discoloration1,6 (Fig. 1).
Magnetic resonance imaging of benign soft tissue neoplasms in adults
2011, Radiologic Clinics of North AmericaCitation Excerpt :There is no gender predilection overall, but there is a 3:1 female predominance for subungual lesions.129 Multiple glomus tumors (nearly 10% of patients) may be present in NF1.130,131 The lesion is most frequently diagnosed between 20 and 40 years of age.
A case of solitary digital glomus tumor associated with neurofibromatosis type 1
2023, SAGE Open Medical Case Reports