Scientific articleDiagnosis and management of asymptomatic renal cell carcinomas in von Hippel-Lindau syndrome
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2009, Surgical Oncology Clinics of North AmericaCitation Excerpt :There are no specific guidelines regarding the type or timing of surgery in patients who have VHL disease. Many management strategies have been proposed, such as observation, nephrectomy, and NSS, depending on the size, number, and location of the tumors and the rate of recurrence.17,18,79,88,96,97 Currently, the treatment options available for hereditary forms of renal cancer are observation with no planned intervention but periodic imaging every 6 to 12 months to monitor tumor growth; NSS to remove discrete renal tumors while sparing normal renal tissue if tumors increase to 3 cm or larger; and unilateral or bilateral nephrectomy to eliminate the risk of developing metastatic cancer.9,11,94
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