Clinical Evaluation of Trimethoprim-Containing Ophthalmic Solutions in Humans
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Update on emerging infections: News from the Centers for Disease Control and Prevention
2002, Annals of Emergency MedicineCitation Excerpt :Topical therapy with sodium sulfacetamide (eg, Bleph 10) has also been commonly used; however, resistance exists among a significant percentage of staphylococcal isolates, and it does not provide adequate coverage against Neisseria species, Serratia marcescens , and Pseudomonas aeruginosa.10 Also, the addition of sulfacetamide to trimethoprim-containing topical ophthalmic solutions (eg, trimethoprim-polymyxin B) has not been shown to produce improved clinical and microbiologic efficacy.11,12 Antibiotic coverage should be extended to cover for Pseudomonas if the patient wears contact lenses (eg, fluoroquinolone or an aminoglycoside).
Ocular methicillin-resistant staphylococcus aureus infections: management difficulties and implications
1995, Clinical Eye and Vision CareAntimicrobial prophylaxis for ophthalmic surgery
1995, Survey of OphthalmologyTreatment of bacterial conjunctivitis in children
2011, Pediatric AnnalsLimitations of current antibiotics for the treatment of bacterial conjunctivitis
2010, Optometry and Vision ScienceManagement strategies for acute infective conjunctivitis in primary care: A systematic review
2007, Expert Opinion on Pharmacotherapy
This study was supported in part by a grant from Research to Prevent Blindness, Inc., New York, New York, and by Burroughs Wellcome Co., Research Triangle Park, North Carolina.
Reprint requests to David W. Lamberts, M.D., Cornea Service, Department of Ophthalmology, Texas Tech University School of Medicine, Lubbock, TX 79430.
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Dr. Buka is in private practice in Cincinnati, Ohio.