References
Durandy A, Kracker S, Fischer A. Primary antibody deficiencies. Nat Rev Immunol. 2013;13(7):519–33.
Warnatz K, Salzer U, Rizzi M, Fischer B, Gutenberger S, Böhm J, Kienzler AK, Pan-Hammarström Q, Hammarström L, Rakhmanov M, Schlesier M, Grimbacher B, Peter HH, Eibel H. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans. Proc Natl Acad Sci U S A. 2009;106(33):13945–50.
Losi CG, Silini A, Fiorini C, Soresina A, Meini A, Ferrari S, Notarangelo LD, Lougaris V, Plebani A. Mutational analysis of human BAFF receptor TNFRSF13C (BAFF-R) in patients with common variable immunodeficiency. J Clin Immunol. 2005;25(5):496–502.
Pieper K, Rizzi M, Speletas M, Smulski CR, Sic H, Kraus H, Salzer U, Fiala GJ, Schamel WW, Lougaris V, Plebani A, Hammarstrom L, Recher M, Germenis AE, Grimbacher B, Warnatz K, Rolink AG, Schneider P, Notarangelo LD, Eibel H. A common single nucleotide polymorphism impairs B- cell activating factor receptor’s multimerization, contributing to common variable immunodeficiency. J Allergy Clin Immunol. 2014;133(4):1222–5.
Germinaro M, Reynolds P, Knight V, Alam R. Association of B-cell activating receptor deficiency with the P21R polymorphism and common variable immunodeficiency. Ann Allergy Asthma Immunol. 2015;115(1):82–3.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
The research leading to these results has received funding from the European Community’s Seventh Framework Programme FP7/2007-2013 under grant agreement n° 201549 (EURO-PADnet HEALTH-F2-2008-201549) and from the Italian Ministerial Grant GR-2010-2315762 to V.L. The research leading to these results also received funding from the “Fondazione C. Golgi”, Brescia.
Conflict of Interest
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
Lougaris, V., Baronio, M., Moratto, D. et al. Monoallelic BAFFR P21R/H159Y Mutations and Familiar Primary Antibody Deficiencies. J Clin Immunol 36, 1–3 (2016). https://doi.org/10.1007/s10875-015-0217-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10875-015-0217-6