Summary
An infant, born to a mother on carbamazepine monotherapy, had a complex cardiac anomaly, consisting of double-outlet right ventricle (DORV), right-sided aorta, pulmonary artery hypoplasia, left ventricular endocardial fibroelastosis, and anatomic evidence of a spontaneously closed muscular ventricular septal defect (VSD). The last finding is one which, to the best of our knowledge, has never been illustrated before.
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References
Alpert SB, Cook DH, Varghese PJ, Rowe RD (1979) Spontaneous closure of small ventricular septal defects.Pediatrics 63:204–206
Becker AE, Anderson RH (eds) (1981)Pathology of congenital heart disease. Butterworth & Co., London. pp 297–307
Briggs GG, Freeman RK, Yaffe SJ (1986) Drugs in pregnancy and lactation. A reference guide to fetal and neonatal risk. 2nd edn. Williams & Wilkins, Baltimore, pp 58/C-59/C
Cheitlin MD, Rabinowitz M, McAllister H, Hoffman JIE, Bharati S, Lev M (1980) The distribution of fibrosis in the left ventricle in congenital aortic stenosis and coarctation of the aorta.Circulation 62:823–830
Hoffman JIE (1968) Natural history of congenital heart disease. Problems in its assessment with special reference to ventricular septal defect.Circulation 37:97–125
Nakane Y, Okuma T, Takahashi R, et al. (1980) Multi-institutional study on the teratogenicity and fetal toxicity to antiepileptic drugs: A report of a collaborative study group in Japan.Epilepsia 21:663–680
Rowe RD, Freedom RM, Mehrizi A, Bloom KR (1981)The neonate with congenital heart disease. 2nd edn. WB Saunders Co., Philadelphia. pp 309–327
Simmons RL, Moller, JH, Edwards JE (1966) Anatomic evidence for spontaneous closure of ventricular septal defect.Circulation 34:38–45
Suzuki H (1969) Spontaneous closure of ventricular septal defects. Anatomic evidence in six adult patients.Am J Clin Pathol 52:391–402
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Nir, A., Weintraub, Z., Oliven, A. et al. Anatomic evidence of spontaneous intrauterine closure of a ventricular septal defect. Pediatr Cardiol 11, 208–210 (1990). https://doi.org/10.1007/BF02238368
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DOI: https://doi.org/10.1007/BF02238368