Skip to main content
Log in

Family history and bilateral primary breast cancer

  • Report
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

Summary

The prevalence of a family history of breast cancer was established in 54 women with bilateral primary breast cancer and 208 women with unilateral disease. Women with bilateral disease had significantly greater prevalence of family history than women with unilateral breast cancer (P<0.01). Compared with the unilateral cancers, a significantly greater proportion of bilateral cancers had first degree affected relatives (P<0.05). Moreover the affected relatives of probands with bilateral disease showed a significantly higher prevalence of bilateral breast cancer compared with the relatives of women with unilateral disease (P = 0.04). The findings suggested that bilateral disease was a characteristic of familial breast cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Broca P: Traité des Tumeurs, Vol. I. P. Asselin, Paris, 1866, p 149

    Google Scholar 

  2. Anderson DE: Some characteristics of familial breast cancer. Cancer 28:1500–1504, 1971

    PubMed  Google Scholar 

  3. Anderson DE: Genetic study of breast cancer: identification of a high risk group. Cancer 34:1090–1097, 1974

    PubMed  Google Scholar 

  4. Henderson BE, Powell D, Rosario I, Keys C, Hanisch R, Young M, Casagrande J, Gerkins V, Pike MC: An epidemiologic study of breast cancer. J Natl Cancer Inst 53:609–614, 1974

    PubMed  Google Scholar 

  5. Morgan RW, Vakil DU, Chipman ML: Breast feeding, family history and breast disease. Am J Epidemiol 99:117–122, 1974

    PubMed  Google Scholar 

  6. Thiessen EU: Concerning a familial association between breast cancer and both prostatic and uterine malignancies. Cancer 34:1102–1107, 1974

    PubMed  Google Scholar 

  7. Harris RE, Lynch HT, Guirgis HA: Familial breast cancer: risk to the contralateral breast. J Natl Cancer Inst 60:955–960, 1978

    PubMed  Google Scholar 

  8. Hubbard TB, Montgomery ALA: Non-simultaneous bilateral carcinoma of the breast. Surgery 34:706–723, 1953

    PubMed  Google Scholar 

  9. Kilgore AR, Bell HG, Ahlquist RE: Cancer in the second breast. Am J Surgery 126:156–160, 1956

    Google Scholar 

  10. Finney GG Jr, Finney GG, Montague ALW, Stonesifer GL, Brown CC: Bilateral breast cancer, clinical and pathological review. Ann Surg 1975:635–642, 1972

    Google Scholar 

  11. Buls JG, Bennett RC, Chan DPS: Bilateral carcinoma of the breast. Aust NZ J Surg 46:336–340, 1976

    Google Scholar 

  12. Sakamoto G, Sugano H, Kasumi F: Bilateral breast cancer and familial aggregations. Prev Med 7:225–229, 1978

    PubMed  Google Scholar 

  13. Hermann JB: Bilateral Mammary Carcinoma. Acta Unio Internationalis Contra Cancrum 11:433–489, 1955

    PubMed  Google Scholar 

  14. Watanatittan S, Ram MD: Non-simultaneous bilateral breast carcinoma. Surgery 75:740–745, 1974

    PubMed  Google Scholar 

  15. Adami H, Hansen J, Jung B, Rimsten A: Characteristics of familial breast cancer in Sweden: absence of relation to age and unilateral versus bilateral disease. Cancer 48:1688–1695, 1981

    PubMed  Google Scholar 

  16. Bailey MJ, Royce C, Sloane JP, Ford HT, Powles T-J, Gazet J-C: Bilateral carcinoma of the breast. Br J Surg 67:514–516, 1980

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chaudary, M.A., Millis, R.R., Bulbrook, R.D. et al. Family history and bilateral primary breast cancer. Breast Cancer Res Tr 5, 201–205 (1985). https://doi.org/10.1007/BF01805995

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01805995

Keywords

Navigation