Summary
A DNA probe (Y-190) is described that specifically hybridizes with repeated DNA sequences in the short arm of the human Y chromosome. The suitability of Y-190 to detect Y-derived DNA is shown in two patients with a 45,X/46,X+marker earyotype and in a third patient previously described as having a 45,X karyotype.
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Müller, U., Donlon, T.A., Kunkel, S.M. et al. Y-190, a DNA probe for the sensitive detection of Y-derived marker chromosomes and mosaicism. Hum Genet 75, 109–113 (1987). https://doi.org/10.1007/BF00591069
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DOI: https://doi.org/10.1007/BF00591069