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A new case of trisomy for the distal part of 13q due to maternal translocation, t(9;13)(p21;q21)

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Summary

The first child of a mother with a balanced translocation (9;13) revealed a trisomy for the distal third of 13q. Clinical signs were microcephaly, hemangiomata, long incurved eyelashes, strabismus, enlarged bridge of the nose, abnormally long philtrum, high-arched palate, low set ears, hexadactyly of the four extremities, umbilical and inguinal hernias, neonatal respiratory distress, psychomotor and growth retardation. The proband presented also male pseudohermaphroditism and trigonocephaly. This last trait is the object of a discussion in which cases of partial trisomy 13q cited in the literature are considered for study of the incidence of this dyscephaly in this particular syndrome.

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Authors and Affiliations

  1. Division de Génétique Médicale, Centre Hospitalier Universitaire Vaudois, Lausanne, (Suisse)

    M. Jotterand & E. Juillard

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  1. M. Jotterand
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  2. E. Juillard
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Jotterand, M., Juillard, E. A new case of trisomy for the distal part of 13q due to maternal translocation, t(9;13)(p21;q21). Hum Genet 33, 213–222 (1976). https://doi.org/10.1007/BF00286845

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  • DOI: https://doi.org/10.1007/BF00286845

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