Summary
A 37-year-old man investigated for infertility had bilateral atrophic testes. Cytogenetic investigations revealed a chromosome complement of 45,XO/46,Xi(Yq)/46,XY. Mechanisms for the origin of the i(Yq) are considered, and the relation of his chromosome constitution to his infertility and hypogonadism are discussed.
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Taylor, M.C., Gardner, H.A. & Ezrin, C. Isochromosome for the long arm of the Y in an infertile male. Hum Genet 40, 227–230 (1978). https://doi.org/10.1007/BF00272306
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DOI: https://doi.org/10.1007/BF00272306