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Insertion/deletion polymorphism within a polyadenylate stretch at the human atrial natriuretic peptides (hANP) gene locus

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Abstract

A novel 8-bp bi-allelic insertion/deletion polymorphism is described within a polyadenylate stretch in the second intron of the human atrial natriuretic peptide gene locus. This new marker is located in the candidate gene for familial susceptibility to hypertension.

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References

  • Greenberg BD, Bencen GH, Seilhamer JJ, Lewicki JA, Fiddes JC (1984) Nucleotide sequence of the gene encoding human atrial natriuretic factor precursor. Nature 312:656–658

    Google Scholar 

  • Masharani U, Nakashima PF, Lim DW, Frossard PM (1988) NsiI and ScaI restriction fragment length polymorphisms at the atrial natriuretic peptides (ANP) gene locus. Hum Genet 80:307

    Google Scholar 

  • Ramasawmy R, Kotea N, Lu CY, Sayada C, Baligadoo S, Krishnamoorthy R (1992) Investigation of the polymorphic ScaI site by a PCR-based assay at the human atrial natriuretic peptides (hANP) gene locus. Hum Genet 90:323–324

    Google Scholar 

  • Ramasawmy R, Kotea N, Lu CY, Sayada C, Baligadoo S, Krishnamoorthy R (1993) A new polymorphic restriction site at the human atrial natriuretic peptide (hANP) gene locus. Hum Genet 91:509–510

    Google Scholar 

  • Yang-Feng TL, Floyd-Smith G, Nemer M, Drouin J, Francke U (1985) The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4. Am J Hum Genet 37:1117–1128

    Google Scholar 

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Ramasawmy, R., Lu, C.Y., Kok-Sun, N. et al. Insertion/deletion polymorphism within a polyadenylate stretch at the human atrial natriuretic peptides (hANP) gene locus. Hum Genet 93, 355–356 (1994). https://doi.org/10.1007/BF00212041

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  • DOI: https://doi.org/10.1007/BF00212041

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