Regular ArticleThe Novel Gene, γ2-COP (COPG2), in the 7q32 Imprinted Domain Escapes Genomic Imprinting
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Cited by (33)
APeg3: Regulation of Peg3 through an evolutionarily conserved ncRNA
2014, GeneCitation Excerpt :First and foremost, APeg3 is the only imprinted antisense transcript expressed from the same (paternal) allele as its sense counterpart. Similar antisense ncRNA counterparts to imprinted genes, such as anti-Rtl1 and Copg2-AS, are selectively expressed from the opposite allele as the sense genes (Ferguson-Smith, 2011; Yamasaki et al., 2000). Secondly, the size of APeg3 is relatively small, 1.5 kb in length, whereas the size of the other imprinted non-coding genes range up to several hundreds of kb in length (Glasgow et al., 2005; Koerner et al., 2009).
Structure and expression of the zebrafish mest gene, an ortholog of mammalian imprinted gene PEG1/MEST
2005, Biochimica et Biophysica Acta - Gene Structure and ExpressionA new frontier for molecular medicine: Noncoding RNAs
2005, Biochimica et Biophysica Acta - Reviews on CancerRegulation by RNA
2003, International Review of CytologyCitation Excerpt :It is transcribed in an opposite orientation relative to MEST, and the 3′-UTRs of the two genes overlap. The antisense transcript originating from intron 20 of this gene COPG2IT1 (COPG2 intronic transcript 1) is paternally expressed in fetal tissues (Yamasaki et al., 2000). In mouse, the corresponding Copg2 and Copg2as2 (Mit1⧸Lb9) genes show reciprocally imprinted expression from maternal and paternal alleles, respectively (Lee et al., 2000).
An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa
2002, Journal of Biological ChemistryCitation Excerpt :Conflicting reports concerning the imprinted status of COPG2 might be explained by the partial overlap of the two adjacent genes (24). To add further complexity to this region, C1T1, an antisense ofCOPG2, originates from intron 20 of COPG2 and is imprinted and paternally expressed in both human and mouse (24,25). Our report focuses on transcripts expressed from the 5′ region of thePEG1 exon 1 that lies 112 kb upstream from the overlapping region and, therefore, are not likely to be associated with theCOPG2 transcription unit.
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