Elsevier

Genomics

Volume 23, Issue 1, 1 September 1994, Pages 158-162
Genomics

Regular Article
The Genes Encoding α2(IX) Collagen (COL9A2) Map to Human Chromosome 1p32.3-p33 and Mouse Chromosome 4

https://doi.org/10.1006/geno.1994.1472Get rights and content

Abstract

We have determined the chromosomal locations of the human and murine genes coding for α2(IX) collagen, a polypeptide subunit of the heterotrimeric type IX collagen molecule. COL9A2 was mapped to human chromosome 1p32.3-p33 using fluorescence in situ hybridization. A single-strand conformational polymorphism within the murine Col9a2 gene was used to map this locus to mouse chromosome 4. We also present new sequence data, which completes the coding information for the human α2(IX) chain and revises the sequence for the chicken α2(IX) chain. This permits comparison of the carboxyl-terminal (NC1) domains of the α1(IX), α2(IX), and α3(IX) chains across several species.

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