Regular ArticleUncoupling Protein 3 and Peroxisome Proliferator-Activated Receptor γ2 Contribute to Obesity and Diabetes in Palauans☆
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Abbreviations used: SNPs, single nucleotide polymorphism(s); RMR, resting metabolic rate; BAT, brown adipose tissue; WAT, white adipose tissue; UCP3-p, uncoupling protein 3 promoter region; PPARγ2, peroxisome proliferator-activated receptor gamma 2; LEPR, leptin receptor; β3AR, beta 3 adrenergic receptor; apo-E, apolipoprotein E; PCR, polymerase chain reaction; RFLP, restriction enzyme fragment length polymorphism; PAGE, polyacrylamide gel electrophoresis; BMI, body mass index; CIOMS, Council for International Organizations of Medical Sciences; HbA1c, hemoglobin A1c; GOT, glutamic oxaloacetic transaminase; GPT, glutamic pyruvic transaminase; γGTP, gamma-glutamyl transpeptidase.
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To whom correspondence may be addressed to Yoshiko Yanagisawa at Medical Chemistry, Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama 350-0288, Japan. Fax: +81-492-82-3618. E-mail: [email protected] or Yasuo Kagawa at Department of Biochemistry, Jichi Medical School, 3311-1, Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi-ken, 329-0498, Japan. Fax: +81-285-44-1827.