Table 1

A summary of epidemiological characteristics of the subjects included in the nested case–control study

ControlsCasesP_difference*
Women (n)1428750
Age at baseline (%)0.70
 <60496 (34.7%)256 (34.1%)
 60–69701 (49.1%)381 (50.8%)
 ≥70231 (16.2%)113 (15.1%)
Age at censoring (%)<0.0001
 <6050 (3.5%)107 (14.3%)
 60–69388 (27.2%)354 (47.2%)
 70–79681 (47.7%)275 (36.7%)
 ≥80309 (21.6%)14 (1.9%)
Birth cohort (%)0.76
 <193028 (2.0%)10 (1.3%)
 1930–1939639 (44.7%)339 (45.2%)
 1940–1949669 (46.8%)354 (47.2%)
 ≥195092 (6.4%)47 (6.3%)
Mean age at baseline (SD)63 (6.2)63 (6.2)
Mean censored age (SD)74 (7.1)68 (6.6)
Mean PRS (SD)
 Overall−0.47 (0.27)−0.39 (0.27)
 Serous−0.55 (0.35)−0.43 (0.36)
Family history of ovarian cancer (%)
Considering only first-degree relatives0.088
 Zero affected relatives1387 (97.1%)718 (95.7%)
 One affected relative41 (2.9%)32 (4.3%)
Considering both first-degree and second- degree relatives0.15
 Zero affected relatives1356 (95.0%)701 (93.5%)
 One or more affected relatives72 (5.0%)49 (6.5%)
Morphology/histotype (%)
Serous489 (65.2%)
 High grade417 (55.6%)
 Low grade23 (3.1%)
 Missing49 (6.5%)
Clear cell29 (3.9%)
Endometrioid56 (7.5%)
Mucinous24 (3.2%)
Others152 (20.3%)
  • 2 tests for differences in the distributions between cases and controls.