Table 3

SNP-based heritability analysis with varying coefficients of relationship (r) thresholds using genotyped SNPS (~246K)

nRelationship (r) thresholdHeritability estimates (SE)PDescription of relationships analysed
15240.050 (0.19)0.5Excludes second, third and fourth cousins and closer
24710.1250.06 (0.11)0.296Excludes first cousins and closer
30060.250.26 (0.09)0.0006Excludes half sibs, aunt/uncle and closer
31680.3750.19 (0.08)0.007Excludes three-quarters sibs or sibling-cousins and closer
5069None0.28 (0.05)1.2×10−10 All relationships included
5069None0.44 (0.06)*2.7×10−14 All relationships included but distant relatives (r<0.05) set to zero
Jointly estimated*
5069None1×10–6 (0.06)1All relationships included
5069None0.44 (0.08)1.4×10–7 All relationships included but distant relatives (r<0.05) set to zero
  • *Heritability estimate calculated using method described by Zaitlen et al.43