Other CPS (non-sex chromosomal aneuploidy syndromes) associated with paediatric ovarian GCTs
| CPS | Subtype of ovarian GCTs (age of onset in years) | Observed cases | First case |
| Cowden syndrome | Dysgerminoma (7) | 1 | Cho et al, 200877 |
| Gorlin syndrome | Dysgerminoma (15) | 1 | Hoorens et al, 201684 |
| BRCA1 germline mutations | Dysgerminoma (16) | 1 | Werness et al, 200078 |
| Down syndrome | Dysgerminoma (11–17) | 4 | Gesmundo et al, 198879 |
| Satgé et al, 200680 | |||
| Hasle et al, 200081 | |||
| Smucker et al, 199982 | |||
| Noonan-like with CBL mutation | Mixed GCT (immature teratoma, dysgerminoma and YST) at 7 years, mature teratoma (14) | 1 | Hanson et al, 201483 |
CPS, cancer predisposition syndrome; GCT, granulosa cell tumour; YST, yolk sac tumour.