SNP | CHR | Mapped gene | Ethnicity | EAF | N studies | Effect allele | βint | SEint | pint | phet |
---|---|---|---|---|---|---|---|---|---|---|
rs6737205 | 2 | BRE | EA | 0.94 | 4 | A | 56.3 | 9.7 | 7.66e−9 | 0.16 |
AA | Did not pass quality control | |||||||||
HSP | Did not pass quality control | |||||||||
rs9830388 | 3 | UBE2E2 | EA | 0.51 | 14 | A | 25.2 | 4.5 | 1.72e−8 | 0.44 |
AA | 0.30 | 5 | A | 18.1 | 11.5 | 0.11 | 0.72 | |||
HSP | 0.55 | 2 | A | −8.2 | 12.4 | 0.51 | 0.44 | |||
rs11867129 | 16 | ABCA3 | EA | 0.09 | 11 | T | 35.7 | 6.9 | 2.57e−7 | 0.05 |
AA | Did not pass quality control | |||||||||
HSP | 0.41 | 2 | T | 4.5 | 13.5 | 0.74 | 0.12 |
Only independent genetic variants with a p value for interaction below 5e−7 are displayed.
AA, African-Americans; ABCA3, ATP binding cassette subfamily A member 3; BRE, brain and reproductive organ-expressed; CHR, chromosome; EA, Europeans; EAF, effective allele frequency; HSP, Hispanic/Latinos; N, number of studies included in the meta-analysis after quality control. phet, p value for heterogeneity between studies; pint, p value of the interaction; SEint, SE of the interaction; UBE2E2, ubiquitin conjugating enzyme E2E 2.