Table 3

rs6581155 tagged SNPs that have been reported to be eQTLs in the region

Study	Zeller et al27					Dixon et al28		Montgomery et al29		Stranger et al30	Dimas et al31
Population	1490 German individuals					206 families of British descent		60 CEU individuals of the HapMap collection		60 individuals of the HapMap collection CEU	80 individuals of Western European origin
Gene	AVIL	XRCC6BP1	TSFM	FAM119B	TSPAN31	FAM119B	TSFM	CYP27B1	FAM119B	FAM119B	FAM119B	FAM119B	FAM119B

Cell type			Monocytes			LCL		LCL		LCL	T-cells	LCL	Fibroblasts

Probe/Transcript	ILMN_20148	ILMN_16915	ILMN_27946	ILMN_12426	ILMN_11441	213861_s_at	212656_at	ENST00000228606	ENST00000300209	GI_24308058-S	ILMN_1723846	ILMN_1723846	ILMN_1723846

	p Value/effect					p Value/effect		p Value/effect		p Value/effect	p Value
SNP
rs6581155										2.1E−10/−0.57
rs10747783						5.00E−21/−0.731	9.00E−13/0.564			7.5E−11/−0.58
rs923829						5.00E−21/−0.731	9.00E−13/0.564			6E−11/−0.58
rs10431552						2.80E−21/−0.745	1.00E−12/0.569			2.1E−10/−0.57
rs2072052						7.70E−19/−689	1.00E−13/0.588			5E−10/−0.56
rs2291617						4.10E−11/−0.62	7.60E−11/0.626			6E−11/−0.58
rs4646536	1.7E−07/−0.021	5E−38/0.11	7.71E−19/0.055	3.34E−236/−0.52	1.4E−11/0.033					2.1E−10/−0.57
rs724834										6E−11/−0.58
rs2069502	1.84E−08/−0.024	4.4E−38/0.11	6.19E−17/0.049	7.78E−221/−0.5	2.29E−12/0.036	7.7E−19/−0.689	1.40E−13/0.583			5.3E−10/−0.56
rs10877013						8.80E−20/−0.711	1.80E−12/0.56			4.1E−10/−0.56	0.000012/−0.481	0.000292/−0.407	0.0000001/−0.571
rs10877011						8.90E−14/−0.612	9.00E−13/0.6	0.00014157/−0.472	0.00013264/−0.474	9.5E−11/−0.57
rs701008						2.30E−12/−0.563	2.30E−11/0.55			1.6E−8/−0.51
rs8181644	1.2E−07/−0.022	3.8E−38/0.11	1.4E−19/0.057	3.9E−234/−0.52	5.5E−12/0.034					2.1E−10/−0.57
rs10877019	4.2E−07/−0.023	6.31E−38/0.11	1.024E−190.058	8.32E−233/−0.52	1.52E−11/0.034					2.1E−10/−0.57
rs11172335										2.1E−10/−0.57
rs703842	1.67E−07/−0.021	2.42E−37/0.11	1.42E−18/0.054	7.5E−235/−0.52	1.41E−11/0.037	7.80E−17/−0.694	2.50E−11/0.568			2.1E−10/−0.57
rs10877015										2.1E−10/−0.57
rs11172333	1.11E−07/−0.023	7.31E−39/0.11	1.74E−19/0.057	2.07E−233/−0.51	5.63E−12/0.035					2.1E−10/−0.57

Zeller et al Genome-Wide Expression analysis performed with Illumina HT-12 v3 BeadChip. Association significance was obtained by ANalysis Of VAriance (ANOVA).
Dixon et al Genome-Wide Expression analysis performed by U133 Plus 2.0 GeneChips (Affymetrix). Association analysis was obtained by fitting a simple regression model to each trait and used a variance component approach to account for correlation between different observed phenotypes within each family.
Montgomery et al Genome-Wide Expression analysis performed by RNA sequencing in an Illumina GAII. Association analysis and multiple testing corrections were conducted by spearman rank correlation and permuting the expression phenotype 10 000 times and summarising the extreme p value distribution for each particular exon, transcript and probe.
Stranger et al Genome-Wide Expression analysis performed with Sentrix Human-6 Expression BeadChip V.1, Illumina. Association significance was obtained by spearman rank correlation with 10 000 permutations of the expression phenotypes.
Dimas et al Gene expression was performed by commercial whole-genome expression array (WG-6 V.3 Expression BeadChip, Illumina). Association analysis and multiple testing corrections were conducted by spearman rank correlation. Thresholds for each gene were assigned after 10 000 permutations of expression values relative to genotypes where the haplotypic (LD) structure was maintained in each interaction.
eQTL, expression quantitative trait loci; LCL, lymphoblastic cell lines.