Location | N | Gender | Age at onset in years | Clinical presentation | Biochemical secretion | Metastatic cases | |||
---|---|---|---|---|---|---|---|---|---|
Male | Female | Median (IQR) | Incidentaloma (image/surgery) | Symptomatic (adrenergic/local mass) | No | Yes | |||
PCC | 200 | 88 | 112 | 45 (36–57) | 41 (36/5) | 100 (96/4) | 5 | 124 | 11 |
p ValuePCC vs PGL | NS | 2.3×10−12 | 0.0083 | ||||||
PGL | 129 | 50 | 79 | 48 (33–60) | 24 (13/11) | 62 (26/36) | 35 | 47 | 18 |
HN-PGL | 61 | 21 | 40 | 52 (39–61) | 5 (2/3) | 29 (2/27) | 28 | 7 | 5 |
p ValueHN-PGL vs T-PGL | NS | NS | 0.012 | ||||||
p ValueHN-PGL vs A-PGL | 0.0057 | 3.6×10−11 | NS | ||||||
T-PGL | 13 | 3 | 10 | 50 (32–62) | 4 (2/2) | 4 (3/1) | 5 | 5 | 5 |
p ValueT-PGL vs A-PGL | NS | 0.0028 | 0.046 | ||||||
A-PGL | 54 | 26 | 28 | 44 (24–59) | 15 (9/6) | 29 (21/8) | 2 | 35 | 7 |
Unlocated PGL | 1 | 1 | 62 | Unknown | Unknown | 1 | |||
Total cases | 329 | 138 | 191 | 46 (35–59) | 65 (49/16) | 162 (122/40) | 40 | 171 | 29 |
A-PGL, abdominal PGL; HN-PGL, head and neck PGL; N, number of cases; NS, not statistically significant; PCC, pheochromocytoma; PGL, paraganglioma; T-PGL, thoracic-PGL; vs, versus.