Putatively functional SNPs correlated with rs3024493
| SNP | Position | r2 with rs3024493 | Variant Location | H3K27Ac mark | DNaseI site | Transcription factor binding site |
|---|---|---|---|---|---|---|
| rs3024505 | chr1:206939904 | 0.947 | Intergenic (1 kb downstream of IL10) | Yes | Yes | NFKB, STAT3, PU.1 |
| rs3024495 | chr1:206942413 | 0.947 | IL10 intronic | Yes | – | – |
| rs3024493 | chr1:206943968 | – | IL10 intronic | Yes | Yes | NFKB, STAT3, POL2 |
| rs3122605 | chr1:206955041 | 0.853 | Intergenic (9.2 kb upstream of IL10) | – | Yes | BATF |
| rs61815643 | chr1:206956116 | 0.732 | Intergenic (10 kb upstream of IL10) | Yes | Yes | NFKB |
rs3024493 was queried against 1000 genome project (1KGP) database for most correlated proxies (r2>0.7). The correlated SNPs were tested and annotated by functional impact using ANNOVAR40 and ENCODE database for multiple functional tracks. The table only lists the tracks with mapping location of correlated variants.
SNP, single nucleotide polymorphism.