Carriers (n=120) | Non-carriers (n=111) | |
---|---|---|
Sex (men/women) | 56/64 | 54/57 |
Age at study inclusion (years; median, range) | 35 (7–80) | 33 (3–69) |
No. diagnosed with melanoma | 39 | 5 |
No. diagnosed with multiple primary melanomas | 20 | 0 |
Age at first melanoma diagnosis (years; median, range) | 39 (16–64) | 45(24–68) |
No. diagnosed with non-melanoma tumours | 13 | 3 |
Gynaecological | 4 | 2 |
Digestive—upper | 2 | 0 |
Haematopoietic or lymphatic | 2 | 0 |
Breast | 1 | 1 |
Respiratory | 1 | 0 |
Skin (non-melanoma) | 1 | 0 |
Digestive—lower | 1 | 0 |
Endocrine | 1 | 0 |
Pancreas | 0 | 0 |
*Baseline is defined as the date when each family’s index case was tested for mutation.