Table 2

Thyroid cancer risk associated with different haplotypes, defined by rs965513 and rs1867277 alleles, at chromosome 9q22

Haplotypers965513rs1867277FrequencyORp Value
CasesControls
1GG0.4130.561Reference
2AA0.4290.2762.139 (1.902 to 2.407)2.19×10−35
3AG0.0970.1111.189 (0.978 to 1.485)0.077
4GA0.0610.0521.612 (1.264 to 2.037)0.0001
  • Haplotype frequencies were estimated using Haploview (http://www.haploview.org/). Only samples with full data at both loci were used for the analyses (761 cases and 6085 controls).