Life table cumulative risks of cancers before the age of 70 (%)
| Sex | Bladder | Ureter and renal pelvis | Urinary tract | Colorectal | Endometrial | |
| MMR mutation carriers and first degree relatives | M | 75 (3.1–11.9) | 3.7 (0.9–6.5) | 11.2 (4.0–18.4) | 43.8 (37.6–50.0) | |
| n=542 | n=13 | n=7 | n=20 | n=141 | ||
| F | 1.0 (0–2.4) | 2.7 (0.3–5.1) | 3.7 (0–7.5) | 38.7 (32.5–44.9) | 27.4 (21.4–33.4) | |
| n=519 | n=2 | n=5 | n=7 | n=112 | n=70 | |
| MLH1 mutation carriers and first degree relatives | M | 10.8 (0–25.2) | 4.8 (0–14.0) | 15.6 (0–39.2) | 57.0 (45.2–68.8) | |
| n=138 | n=2 | n=1 | n=3 | n=51 | ||
| F | 0 | 2.4 (0–7.2) | 2.4 (0–7.2) | 50.4 (37.0–63.8) | 19.5 (8.5–30.5) | |
| n=148 | n=0 | n=1 | n=1 | n=40 | n=12 | |
| MLH2 mutation carriers and first degree relatives | M | 12.3 (4.3–20.3) | 5.9 (0.7–11.1) | 18.2 (5.0–31.4) | 43.5 (34.7–52.3) | |
| n=248 | n=10 | n=5 | n=15 | n=65 | ||
| F | 2.6 (0–3.8) | 5.8 (0–11.6) | 8.4 (0–15.4) | 47.4 (36.8–58.0) | 26.1 (16.9–35.3) | |
| n=213 | n=2 | n=4 | n=6 | n=51 | n=28 | |
| MLH6 mutation carriers and first degree relatives | M | 1.3 (0–3.9) | 1.3 (0–3.9) | 2.6 (0–7.8) | 31.0 (20.0–42.0) | |
| n=156 | n=1 | n=1 | n=2 | n=25 | ||
| F | 0 | 0 | 0 | 22.1 (13.1–31.1) | 32.7 (22.3–43.1) | |
| n=158 | n=0 | n=0 | n=0 | n=21 | n=30 | |
| Proven and obligate MMR mutation carriers | M | 16.4 (6.4–26.4) | 91 (2.1–16.1) | 25.5 (8.5–42.5) | 70.1 (60.9–79.3) | |
| n=226 | n=12 | n=7 | n=19 | n=108 | ||
| F | 1.9 (0–4.9) | 5.4 (0.2–10.6) | 7.3 (0–15.5) | 56.6 (47.4–65.8) | 35.4 (26.8–44.0) | |
| n=232 | n=2 | n=5 | n=7 | n=89 | n=53 | |
| Dutch population | M | 1.79 | 0.10 | 1.89 | 2.70 | |
| F | 0.45 | 0.04 | 0.49 | 2.14 | 1.05 |
F, female; M, male; MMR, mismatch repair.