Multivariate logistic maximum likelihood estimates of segregation models for inheritance of ankylosing spondylitis in family C
| Multifactorial only | Multifactorial+commingled | Multifactorial+Mendelian | Multifactorial+free τ’s | Multifactorial+dominant | Multifactorial+recessive | |
| qA | (1.0) | 5.13×10−3 | 0.68 | 0.84 | 0.70 | 0.97 |
| τAA | … | … | (1.0) | 0.0 | (1.0) | (1.0) |
| τAB | … | … | (0.5) | 1.0 | (0.5) | (0.5) |
| τBB | … | … | (0.0) | 0.0 | (0.0) | (0.0) |
| SuscAA | … | 0 | 7.67×10−30 | 7.36×10−35 | 4.41×10−22 | 8.49×10−55 |
| SuscAB | … | 0.14 | 7.61×10−26 | 0 | 4.41×10−22 | 0.50 |
| SuscBB | 0.17 | 0.14 | 0.51 | 0.54 | 0.56 | 0.50 |
| ρresid | 1.67 | 8.08 | 4.00 | 4.02 | 4.06 | 3.87 |
| -2lnL | 47.16 | 32.15 | 26.38 | 22.36 | 26.44 | 28.13 |
| Akaike’s AIC | 51.16 | 42.15 | 36.38 | 32.36 | 34.44 | 36.12 |
Test H01: no major gene effect, χ2 = 20.78, df = 3, p = 1.17×10−4.
Test H02: no transmission of major gene effect, χ2 = 9.79, df = 3, p = 0.02.
Test H03: Mendelian transmission, χ2 = 4.02, df = 3, p = 0.26.
Test H04: Mendelian transmission and dominant inheritance, χ2 = 0.06, df = 1, p = 0.81.
Test H05: Mendelian transmission and recessive inheritance, χ2 = 1.75, df = 1, p = 0.19.