Table 2 Association analysis of IRF5 polymorphisms with multiple sclerosis in the Finnish trios
PolymorphismAssociated alleleObs-Exp*p Value
rs729302A+0.047
rs4728142A+0.035
rs3757385G+0.53
CGGGG indelin+0.056
rs2004640T+0.54
rs3807306T+0.012
rs10954213A+0.010
rs11770589A+0.070
rs2280714T+0.30
rs12539741T+0.74

  • *Difference between observed and expected transmissions of the associated allele; + denotes increased transmission to affected offspring; p values below 0.05 are indicated in bold.