Table 6 Array CGH findings in 11 carriers of reciprocal translocations associated with phenotypic abnormalities*
Patient (total no of breakpoints before and after array CGH)Deleted regionsNon-deleted probe (Mb)Deletion start (Mb)Deletion end (Mb)Non-deleted probe (Mb)Deletion size (Mb)
1 (2,3)Del(7q22.3–q31.1)105.5105.9113.7113.87.8
2 (2,3)Del(1q24)160.6160.8165.8165.94.9
3 (2,3)Del(2)(q33.1)199.84199.90203.15203.163.2
4 (2,3)Del(2)(q22.3–q23.1)148.14148.18149.32149.331.1
5 (2,4)Del(6)(q14.3–15)85.2886.3890.5690.594.2
6 (2,4)Del(2)(p22.3–p21)33.5633.6141.9742.328.4
7 (2,8)Del(2)(q23.3–q24.1)152.52152.55157.12157.174.6
Del(2)(q31.1)175.8175.87177.02177.081.7
Del(9)(pter–p24.2)2.903.193.2
8 (2,4)Del(6)(q12)65.1265.1467.2267.312.1
Del(7)(pter–p22.3)2.372.382.4
9 (2,4)Del(4)(p15.2)27.2427.2527.51627.880.6
10 (2,3)Del(9)(p23–p22.2)13.4913.8617.3317.623.4
11 (2,3)Del(17)(q24.3)65.2265.3766.9167.021.5
  • *Array CGH resolution was about 100 kb (kit 44BB, Agilent) in all patients except 3, 4 and 8, which were studied at a resolution of about 20 kb (kit 244A, Agilent).

  • Deletions away from the breakpoints are in italics.

  • Map positions refer to the Genome Assembly May 2004 (Build 35).