Table 2

 Mean age of first tumour onset in p53 mutation carriers according to the MDM2 SNP309 or p53 codon 72 genotypes

GenotypeNo. of patientsMean age (years)*
*Of first tumour onset.
MDM2 SNP309 T/T 1429.9
T/G 1917.8
G/G 823.3
T/G+G/G 2719.6
p53 codon 72 polymorphism Arg/Arg 1821.1
Arg/Pro 2022.5
Pro/Pro 834.4
Arg/Pro+Arg/Arg 3821.8