Association of PRKAA2 haplotypes (frequency>2%) with lipid profile
| Haplotype | Freq. (%) | ApoB | Total cholesterol | LDL- cholesterol | HDL-cholesterol | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β (SE) | p Value | Variance explained (%) | β (SE) | p Value | Variance explained (%) | β (SE) | p Value | Variance explained (%) | β (SE) | p Value | Variance explained (%) | ||
| Apo, apolipoprotein; Freq, frequency. | |||||||||||||
| *The most common haplotype with which the others were compared. | |||||||||||||
| 11112* | 45.7 | — | — | — | — | — | — | — | — | — | |||
| 21221 | 34.7 | −0.038 (0.019) | 0.034 | — | −0.257(0.071) | <.001 | — | −0.235 (0.069) | 0.001 | — | −0.006 (0.025) | NS | — |
| 22121 | 10.5 | −0.022 (0.029) | NS | — | −0.082(0.111) | NS | — | −0.025 (0.107) | NS | — | −0.111 (0.039) | 0.005 | — |
| 11211 | 2.3 | 0.032 (0.058) | NS | — | 0.337(0.229) | NS | — | 0.248 (0.221) | NS | — | 0.0421 (0.080) | NS | — |
| 12111 | 2.3 | 0.037 (0.061) | NS | — | 0.157(0.244) | NS | — | −0.177 (0.239) | NS | — | 0.067 (0.0834) | NS | — |
| Overall | — | — | NS | — | — | 0.002 | 0.76 | — | 0.01 | 0.75 | — | 0.05 | 0.59 |