Age specific cancer risks in BRCA2 mutation carriers
| Location | <65 years of age | ⩾65 years of age | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Obs | Exp | RR | 95% CI | Obs | Exp | RR | 95% CI | |||||||||
| See Methods section for estimating RR. *Prostate cancer risk estimated before and below 73 years of age. For all presented cancer sites, p for difference is <0.001. | ||||||||||||||||
| All cancers | 95 | 29.4 | 5.5 | 0.7 to 1.4 | 104 | 170.5 | 0.2 | 0.2 to 0.3 | ||||||||
| Pharynx | 2 | 0.3 | 15.7 | 1.8 to 56.6 | 2 | 0.8 | 4.2 | 0.5 to 14.9 | ||||||||
| Colon | 8 | 1.8 | 8.0 | 3.4 to 15.7 | 12 | 14.7 | 0.6 | 0.3 to 1.1 | ||||||||
| Pancreas | 8 | 0.4 | 37.1 | 16.0 to 73.1 | 7 | 4.0 | 2.5 | 1.0 to 5.2 | ||||||||
| Prostate* | 12 | 2.7 | 8.0 | 4.1 to 14.0 | 12 | 10.9 | 1.2 | 0.6 to 2.1 | ||||||||