Table 3

Apoptosis assays

Plasmid		*PARP (%)**		Annexin V*
*Two representative assays, performed blind.
Vector		<1		−
Wt		25		++
P24S		25		++
E153K		25		++
Q564H		1		−
C645R		1		+
R658C		25		++
V695L		1		+
I738V		25		++
S761N		1		−
N295S		N/A		+
K312N		N/A		−
C557S		N/A		−