Genotype distribution of TNFβ and TNFα −308 variants in group A (n = 27) compared to group B (n = 102) and reference groups
| Genotype | Group A (n, %) | Group B (n, %) | Reference (n, %)*† | |
|---|---|---|---|---|
| Reference groups23: *group1 TNFβ gene (n = 252); †group 2 TNFα −308 gene (n = 233). | ||||
| TNFβ | 1/1 | 1 (3, 7%) | 18 (17, 7%) | 35 (13, 9%) |
| 1/2 | 8 (29, 6%) | 39 (38, 2%) | 98 (38, 9%) | |
| 2/2 | 18 (66, 7%) | 45 (44, 1%) | 119 (47, 2%) | |
| Total | 27 (100%) | 102 (100%) | 252 (100%) | |
| p Value | p<0.06 | p<0.66 | ||
| TNFα promoter −308 | 1/1 | 19 (70, 4%) | 68 (66, 7%) | 151 (64, 8%) |
| 1/2 | 7 (25, 9%) | 29 (28, 4%) | 69 (29, 6%) | |
| 2/2 | 1 (3, 7%) | 5 (4, 9%) | 13 (5, 6%) | |
| Total | 27 (100%) | 102 (100%) | 233 (100%) | |
| p Value | p<0.92 | p<0.94 | ||