Marker† | Heterozygosity‡ (%) | Haplotype* | Genotype for CEPH individual 134702 | ||||
---|---|---|---|---|---|---|---|
A | B | C | D | ||||
*We only report here those cases in which the haplotype associated with the deletion could be determined unambiguously. Allele sizes were determined by DNA sequencing of a control sample, which was used as a standard in genotyping assays. To allow other laboratories to compare their data with those reported in this work, we provide allele sizes for individual 134702, available from CEPH.25 | |||||||
†Relative order and physical distances are as follows: (TG)n – 110 kb – (GAAA)n – 9 kb – deletion proximal breakpoint – 232 kb – deletion distal breakpoint – 6 kb – D13S1853 – 60 kb – D13S1830. | |||||||
‡Calculated from 100 Spanish control chromosomes. | |||||||
(TG)n | 65 | 208 | 204 | 206 | 208 | 206/208 | |
(GAAA)n | 79 | 209 | 209 | 209 | 209 | 209/216 | |
D13S1853 | 66 | 204 | 204 | 204 | 204 | 202/202 | |
D13S1830 | 71 | 153 | 153 | 153 | 156 | 153/156 | |
Number and geographical distribution of haplotypes (n = 14) | 6 Spain | 1 Spain | 1 Spain | 2 Spain | |||
2 UK | 1 UK | ||||||
1 Italy | |||||||
Total: 9 | Total: 2 | Total: 1 | Total: 2 |