Phenotype | IL10-1082 genotype | Test statistic | p value | |||||||
---|---|---|---|---|---|---|---|---|---|---|
GG (n = 64) | GA (n = 119) | AA (n = 51) | ||||||||
Group distributions for age at diagnosis and duration of disease are shown for the three genotypes. Only risk factors with a p value <0.2 are shown. These were further tested in multivariate analysis. | ||||||||||
Group distribution (years) | F | |||||||||
Mean (SD) age at diagnosis | 29.4 (1.7) | 27.6 (1.3) | 28.9 (1.5) | 0.46 | 0.63 | |||||
Mean (SD) disease duration | 12.7 (0.9) | 12.7 (0.7) | 11.0 (0.9) | 1.28 | 0.28 | |||||
Genotype distribution (n (%)) | ||||||||||
Any CD surgery | χ2 | |||||||||
No | 11 (17.2) | 24 (20.2) | 16 (31.4) | |||||||
Yes | 53 (82.8) | 95 (79.8) | 35 (68.6) | 3.73 | 0.16 | |||||
Phenotype | ||||||||||
Stricturing | 17 (27.4) | 40 (34.2) | 13 (25.5) | |||||||
Penetrating | 31 (50.0) | 40 (34.2) | 16 (31.4) | |||||||
Non-stricturing | 14 (22.6) | 37 (31.6) | 22 (43.1) | 8.26 | 0.08 | |||||
Stricturing | ||||||||||
Never | 30 (48.4) | 54 (46.2) | 34 (66.7) | |||||||
Ever | 32 (51.6) | 63 (53.8) | 17 (33.3) | 6.27 | 0.04 |