LOH data in reported cases of BRCA1/BRCA2 double heterozygosity
| Breast cancer tissue (case No) | Ovarian cancer tissue (case No) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 13 | 20 | 21 | 24a | 24b | 24c | 25 | 1 | Total | 13 | 20 | 1 | Total | |
| *Predominant loss of mutant allele. | |||||||||||||
| LOH, loss of heterozygosity. | |||||||||||||
| LOH BRCA1 | − | + | − | − | − | + | − | + | 3/8 | − | + | + | 1/3 |
| LOH BRCA2 | − | − | + | + | + | − | − | +/− | 3/7 | − | + | −* | 1/2 |