Families | Individuals | Total offspring | Female offspring | p Value | |
---|---|---|---|---|---|
*Includes 6174delT. | |||||
All BRCA2 | 99 | 174 | 268 | 145 (54.1%) | |
6174delT | 47 | 71 | 117 | 72 (61.5%) | 0.032 |
Other BRCA2 | 52 | 103 | 151 | 73 (48.3%) | |
Exons 1–11* | 82 | 138 | 201 | 118 (58.7%) | 0.009 |
Exons 12–27 | 17 | 36 | 67 | 27 (40.3%) | |
Exons 1–11 excluding 6174delT | 35 | 67 | 84 | 46 (54.7%) | 0.077 |
Exons 12–27 | 17 | 36 | 67 | 27 (40.3%) |